HPV types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 (DNA qualitative genotyping, swab/F)

We remind you that independent interpretation of the results is unacceptable, the information provided below is for reference purposes only.

HPV (Human Papillomavirus) genotyping analysis detects DNA of high-risk oncogenic types: 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59. These types are associated with the development of precancerous lesions and cervical cancer. HPV is primarily transmitted through sexual contact and may persist in cervical epithelium without noticeable symptoms.

Indications

• Cervical cancer screening
• Investigation of abnormal cytology (Pap test) results
• Suspected HPV infection or presence of anogenital warts
• Follow-up after treatment of HPV-associated cervical lesions
• Assessment of risk for cervical precancerous changes
• Preventive examination in women

Procedure

Sample collection is performed by a gynecologist in a clinical setting.
A special brush is used to collect cells from the surface of the cervix and the cervical canal.
The procedure takes a few minutes and may cause mild discomfort but is generally not painful.

Method of testing

Molecular genetic method - PCR (polymerase chain reaction) for qualitative detection and genotyping of Human Papillomavirus DNA.
It allows identification of high-risk oncogenic HPV types.

Preparation

• Not performed during menstruation
• Avoid sexual intercourse for 48 hours before testing
• Do not use vaginal creams, suppositories, or tampons for 48 hours before testing
• Avoid vaginal douching
• Ideally performed 48–72 hours after gynecological procedures (colposcopy, transvaginal ultrasound)
• Avoid urination 2–3 hours before sample collection
   

Sources:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215574/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683586/
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0158184

IMPORTANT!

It is crucial to remember that the information provided in this section is not intended for self-diagnosis or self-treatment. If you experience any pain or exacerbation of a condition, you must consult a doctor for diagnostic testing and appropriate treatment. Only a qualified healthcare professional can make an accurate diagnosis and determine the appropriate course of treatment. To obtain the most accurate and consistent evaluation of test results, it is recommended to have them performed at the same laboratory. This is because different laboratories may use varying methods and units of measurement for similar tests.