Glutamate

Glutamate (F336) is a food additive classified as a flavor enhancer, widely used in the food industry (including monosodium glutamate). Allergological testing is aimed at detecting sensitization to this substance by measuring specific immunoglobulin E (IgE) in the blood serum.

Although true IgE-mediated allergy to glutamate is rare, some patients may experience hypersensitivity reactions manifested by various clinical symptoms.

Indications

• Suspected food hypersensitivity to products containing flavor enhancers;
• Appearance of symptoms after consuming foods with glutamate (headache, skin redness, flushing, tachycardia);
• Skin manifestations: itching, rash, urticaria;
• Respiratory symptoms (nasal congestion, difficulty breathing);
• Differential diagnosis between allergic and non-allergic reactions to food additives;
• Comprehensive investigation in suspected food allergy cases.

Procedure

• Venous blood is collected;
• The laboratory determines the level of specific IgE to glutamate (F336);
• The procedure takes a few minutes and is well tolerated by patients;
• Results allow assessment of the presence or absence of sensitization to this allergen;
• The test result is usually available within 1–3 working days.